Wake Up! 5 Best OTC Eye Drops For Dry Eyes That Doctors Recommended To Use

​​In our commitment to provide you with only the best available products, we reviewed 5 of the best eye drops and have come up with what we think is the best eye drops for ​dry eyes ​in ​over-the-counter market. This list is based on hours of extensive researches with the products ranked according to their effectiveness, their eye condition, and their value for money. All products are doctor recommended to us

At A Glance: Our Choices for The Best Eye Drops for ​dry eyes

If you are looking for some products made of natural ingredients but not too pricey, take a look at Similasan Complete Dry Eye Relief, you might like this one.

Mild case of dry eyes? don't worry! this Visine Dry Eye Drop won’t make you disappointed, plus the price is quite affordable for such a high performance

Optrex Intensive is your ideal drops as it can help you treat dry eye symptoms while you don’t need to remove your contact lenses. This drop is suitable for contact lenses wearers

This Optique 1 Eye Drops from the world leader in homeopathic in the USA will be your best choice if your eyes usually react with other synthetic eye drops. This drops contains no harsh chemicals, it’s totally safe to use for children up to 2 years old too

Anyone has used antibacterial Manuka honey before must know about this amazing treatment. If you want to protect your eyes from infection, go for this Optimel Manuka with its Manuka honey preparation.

​Now let's review the 5 best products for frequent dry eyes​:


​Key Features (*)

#1 - Similasan

  • ​Vasoconstrictor free
  • ​Size: 0.33 fl oz (10ml)
  • ​Natural active ingredients
  • ​Original Swiss formula

#2 - Visine Dry Eye

Visine Dry Eye Relief Lubricant Eye Drops
  • ​Brand: 60 year experience
  • ​Size: 1/2 fl oz (15ml)
  • ​Used in different environment
  • ​Effective Relief

#3 - ​Optrex

  • Type: ​​Rewetting Eye drops
  • ​Size: 0.34 oz (10 ml)
  • ​Suitable use with contact lenses
  • ​Suitable for everyday use

#4 - ​​Optique 1

  • ​Type: ​ Homeopathic Eye Drops
  • ​Size: 0.013 fl oz/dose
  • ​Can use with other medications
  • No vasoconstrictor or astringents

#5 - ​Optimel

Optimel Manuka Honey Eye Drops
  • Type:​ Artificial Tear Drops
  • ​Size: 0.34 oz (10 ml)
  • ​Treat Chronic Dry Eye
  • ​Stabilize Eye Surface

(*) Note: The description and specifications of products are updated as the time of editor's article. However they are the subject for changes over time. Please read the product ​descriptions carefully before you buy any recommended product.

Here, the 5 ​best tear drops for​ ​eye dryness that ​you can display in your ​medicine cabinet with pride.

​#1 ​​Similasan Complete Eye Relief Eye Drops

This product comes with 2 bottles that will provide you with temporary relief not only from dry eyes but also from other conditions like red eyes, itchy or burning sensation. Similasan eye drops contains some natural ingredients to trigger the body's defense mechanism.

The eye drops has been used and recommended by doctors for over 35 years. It is manufactured by a leading Swiss brand that emphasizes on using natural active ingredients for making family-friendly products


​​Similasan does not contain vasoconstrictors, a chemical substance that can cause side effects for your eyes. This product is completely safe for using on a daily basis.

​What we like:

  • ​Family-friendly products
  • ​Suitable for many symptoms
  • ​No vasoconstrictors or harsh chemicals
  • ​Prepared with natural ingredients

​​What we didn't like

  • ​Feel a little discomfort
  • ​Causes itchy in some cases

#2 ​​Visine Dry Eye Relief Lubricant Eye Drops

Visine Dry Eye​ comes with two sizes for a pack of one or two 0.5 fluid ounce bottles. Visine is suitable for frequent dry eyes, and it can relieve symptoms caused by a condition such as burning, gritty or irritation.

Ingredients found in the formula are similar to those in natural tears like glycerine, hypromellose, and polyethylene glycol. These medicaments are often used to moisturize and soothe the surface of the eyes and bring a relief effect instantly.​

Visine Dry Eye Relief Lubricant Eye Drops

Visine is suitable for occasional and mild case of dry eyes, and it also provides further protection from infection as well as other eye problems.

​What we like:

  • ​Long-lasting effect
  • ​Value size
  • ​Well-known brand
  • ​Suitable for frequent dry eyes

​​What we didn't like

  • ​Contains preservative
  • ​Slight burning sensation

#3 ​Optrex Intensive Eye Drops

Optrext Intensive is one solution to your dryness condition. This product is designed to help you cope with common issues of modern lifestyle from frequent traveling, working in an air-conditioned cubical, extended long working hours on digital devices, and polluted air.

Th​e product can be used on a regular basis to provide protection for your eyes throughout the day. It immediately refreshes and relieves dry eyes every time when the condition occurs due to old age, hot climate or allergy.


The brand is trademarked by Optrext Ltd, a UK based company specializes in developing products for eye health. This eye drops can also be used while wearing contact lenses.

​What we like:

  • ​Free-preservative
  • ​Used with contact lenses
  • ​Fast eye relief effect
  • ​Well-trusted UK brand

​​What we didn't like

  • ​A little itching after 1 or 2 drops
  • ​May have dermatitis for sensitive skin

#4 ​Boiron Optique 1 Eye Drops

The last product that makes it to our list is from the world leader in homeopathic in the USA. I am talking about Optique 1. This eye drops contains 20 single use sterile doses that work naturally with your body.

Optique 1 ​eye drops is suitable for sensitive eyes if your eyes often respond with harsh chemicals, which makes it an excellent choice for treating frequent dryness.


Optique 1 bring fast and immediate relief effect to your eyes and soothe burning eyes with no drug interaction. The drops is single use and contain no preservatives. It can be used safely for children up to 2 years old.

​What we like:

  • ​No preservative
  • ​Work naturally with body
  • ​Suitable for children up to 2 years old
  • ​No harsh chemicals in the ingredient

​​What we didn't like

  • ​Pricey for the number of dose
  • ​Causes blurry vision when overused

#​5 ​Optimel Manuka Honey Eye Drops

Straight to the point, this product is used best for chronic dry eye, blepharitis and soreness. ​

When the drops contact the eyes, it provides an environment that eliminates the bacteria potentially living on the surface and creates a micro-environment that supports healing damage as well we preventing infection.

Optimel Manuka Honey Eye Drops

One of the ingredients is an antibacterial Manuka honey that helps to provide the best remedy for moderate and severe dry eyes.​ 

Manuka honey, derived from flowers of the Manuka bush (Leptospermum scoparium), in particular has been noted for its bactericidal activity. Many types of honey contain hydrogen peroxide as the main antimicrobial mechanism, whereas the antibacterial effects of Manuka honey are considered to be primarily from its substantial content of methylglyoxal (MGO), a compound found in only certain honeys.

Application of Optimel Manuka 2 to 3 times on a daily basis to reduce the Colony Forming Unit in eyes, and avoid possibilities of contracting to eye infection.

​What we like:

  • ​Reduce lid margin redness
  • ​Contain antibacterial Manuka Honey
  • ​Suitable for severe dry eyes
  • ​Healing damage on the tears firm

​​What we didn't like

  • ​Containing preservative
  • ​Costly

Comparisons Chart: Which is the Best Eye Drops ​For Dry Eyes?


Best Overall

​2nd choice

3rd choice

4th choice

5th choice

Top-Rated ​

Eye Drops

For ​Dry Eye 


Visine Dry Eye Relief Lubricant Eye Drops
Optimel Manuka Honey Eye Drops





​​Optique 1


​Editor's rating







​Use for

​​red​, itching, burning, stinging, irritated ​& watering eyes

​Dry ​eye

gritty eyes

burning irritation

​dehydrate dry, irritated or tired eyes

​Dry, Itchy Gritty Eyes Red, Burning ​ Tired Eyes

​Dry eye:

sore, irritated eyes ​& eyelids


0.33 oz (10mL)

​​1/2 oz (15mL)

​​​0.34 oz (10mL)

​0.013 oz/dose

​​​​​0.34 oz (10mL)





​Pack 10-30 doses

​One pack

​Get started

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Dry eyes can be irritated if it occurs frequently, although synthetic drops can bring a temporary relief effect. It is essential to understand what causes dryness in your eyes and take action to prevent it from happening.

However, sometimes chronic dry eyes is caused internally by many factors, and this is when eye drops can help to tackle the problems. To conclude, we decide to pick out ​Similasan Complete Eye Relief Eye Drops for you as the best product for frequent dry eyes.

​The reason why we choose this product is because not only it helps to relieve dry eye symptoms, but also it is a friendly-family product. Besides, it also does not contain any preservative or hash chemical that might cause side effects for your children.

It's all about the best eye drops for dryness. What do you have in your mind now? 

We would love to hear from your personal experience when using this product, don't forget to leave us a comment below.


Giới thiệu: Bo Yong

I'm the founder and owner of Thank Your Eyes. I have been nearsighted since I was a child, so I had eye surgery with LASIK method but it was damaged so I had to undergo additional surgery. Fortunately, this time my eyes were clear again. With this blog, I want to share my experiences with anyone who is having eye problems and wants to have healthy eyes.

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